Author: teamin

In the realm of pharmaceutical and chemical manufacturing, achieving high-quality granulation is paramount. Key to this process are two critical factors: process robustness and high efficiency. High-shear mixer granulators are specifically designed to meet these needs, offering superior mixing capabilities within a short timeframe and providing a wide process window in terms of mixing duration. Key Benefits of High-Shear Mixers Higher Yields These mixers are engineered to prevent wall caking and clogging. This design ensures controlled discharging, contributing to robust and secure processing. High Batch Variability The unique positioning and geometry of the mixing tools, along with versatile operating modes, …

Dwell time, a critical parameter in tablet manufacturing, wields a substantial influence on tablet quality and the overall production process. In this comprehensive exploration, we delve into the concept of dwell time, its profound impact on tablet compression, and the multifaceted factors that it influences. Unveiling the Essence of Dwell Time Dwell time, within the context of tablet compression, refers to the duration during which the punches of the tablet compression machine cease their vertical motion, reaching maximum penetration within the die beneath the primary compression rollers. This critical phase occurs as the compression rollers make contact with the flat …

Tableting represents a range of processes used to transform a powdered formulation into solid tablet form. Formulation Phase The initial phase involves creating the tablet’s formulation, a critical step, particularly for pharmaceutical-grade tablets containing active pharmaceutical ingredients (APIs). Here, meticulous attention to ingredient ratios is crucial. Excipients or “fillers,” including binders, diluents, lubricants, and disintegrants, are often present. The percentage of API in the final tablet is known as the “drug load.” Granulation Techniques: To ensure the optimal particle size distribution for effective tablet formation, the powder material often undergoes granulation. There are two primary granulation methods: Wet Granulation: This …

In pharmaceutical industries, the need to maintain the sterility of products is a key requirement. Sterile packaging systems eliminates the risks of microbial contamination of the product or packaging without compromising on the quality of the goods being packed or transported. The process of sterilisation involves the use of a sterile manufacturing vessel, a washing machine for bottles, vials, ampoules etc.., sterile blending vessels, and a depyrogenation tunnel, among others. When it comes to packaging parenteral products, there are six primary sterile packaging systems in use today. Each of these systems offers unique advantages and is chosen based on various …

 Pharmaceutical containers are designed to protect pharmaceutical drugs like injectables or dry powder injectables from external influences. These containers not only store the products being manufactured but also keep it from contamination. What is Ampoule? The ampoule, with its roots dating back to ancient Rome, where it was first used around the 1st century AD, is a small, sealed-neck single-dose vial. Historically, it has been employed across various cultures and regions. However, it gained prominence in the pharmaceutical field during the 19th century. Typically made of glass (though plastic variants exist), ampoules ensure sterility by sealing the neck with an …

At the core of our aseptic filling machine, collection lies a crucial component – our range of vial filling machines. Designed to accommodate both small-scale and large-scale batch requirements, these filling machines serve impeccably in product development as well as clinical studies. Whether you are engaged in full-fledged commercial production or contributing to vital vaccination initiatives, our production lines are meticulously engineered to span output capacities ranging from 150 to 600 units per minute (equivalent to 9,000 to 36,000 units per hour), offering unparalleled adaptability to meet your specific needs Our cutting-edge automatic vial filling equipment is meticulously designed to …

1) What are capsules? Capsules are typically made of gelatin or other suitable materials and contain the active pharmaceutical ingredient (API) in the form of a powder, granules, or pellets. A capsule filler machine & accessory equipment for capsule filling machine ensures that the required dosage is filled within the capsule. The capsule shell is designed to enclose the drug and facilitate its ingestion. 2) Capsule types Capsules are oral dosage forms with hard or soft shells, available in various shapes and sizes, containing a single dose of one or more active ingredients. The process of encapsulation can be used …